Article Type
Article
Abstract
Introduction: Langerhans cell histiocytosis is a rare disease that can present as uniorgan or multiorgan involvement. More than 60% of cases of Langerhans cell histiocytosis can present with head and neck lesions. Tissue biopsy is mandatory for confirming the diagnosis beside clinical and radiological findings.
Case report: The authors present a 9‑year‑old boy who initially presented with oral cavity lesion and gum swelling for 3‑week period, who subsequently showed severe diffuse lung infiltration complicated with pneumothorax and pituitary stalk involvement with diabetes insipidus.
Diagnosis was confirmed with oral lesion biopsy.
Conclusion: Oral lesions are easily approachable, and biopsy can be done under local anesthesia, with minor medical and cosmetic complication. Any initial aggressive surgical intervention should be avoided.
Keywords: Diabetes insipidus, langerhans cell histiocytosis, oral lesions, tissue biopsy.
Recommended Citation
Kasim Aljanabi KS.
Case Report: A rare case report of Langerhans cell histiocytosis (Hand–Schuller–Christian disease) and review of literature.
Pan Arab J. Rhinol.
2020;
10 : 136-138.
Available at:
https://pajr.researchcommons.org/journal/vol10/iss2/16
DOI: https://doi.org/10.4103/pajr.pajr_21_20
