Article Type
Article
Abstract
Objective
This cohort prospective intervention study was initiated to investigate the effectiveness of mucolytic nasal wash on postoperative healing after endoscopic nasal surgery (ENS).
Patients and methods
A total of 60 patients of both sexes, above 21 years, underwent ENS, who were randomly distributed into two groups according to inclusion and exclusion criteria, with 30 patients each. Postoperative hypertonic saline nasal irrigation was used for group A, and in addition of N‑acetylcysteine (NAC) in group B. Measurement of outcome was done using modified Symptom based Modified Sino‑Nasal‑Outcome Test score‑22 and Lund–Kennedy endoscopic score.
Results
We noticed that nasal irrigation with combined hypertonic saline with NAC is effective in reducing postoperative symptoms scores and endoscopic scores for patients following ENS or functional endoscopic sinus surgery.
Conclusion
NAC combined hypertonic saline irrigation had significant better results than standard hypertonic saline nasal irrigation only following endoscopic sinus surgery, significantly improving patient’s quality of life.
Keywords:
endoscopic sinus surgery, functional endoscopic sinus surgery, hypertonic saline, N‑acetylcysteine
Recommended Citation
Rabie HM, Saleh AS.
Postoperative nasal irrigation with hypertonic saline versus adding mucolytic agents: cohort prospective study.
Pan Arab J. Rhinol.
2021;
11 : 47-53.
Available at:
https://pajr.researchcommons.org/journal/vol11/iss1/8
DOI: https://doi.org/10.4103/pajr.pajr_35_20
