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Article Type

Original Study

Subject Area

Rhinology, Endoscopic sinus surgery

Abstract

Background Nasal polyps as a type of nasal masses usually present with nasal obstruction and smell disorders. There is high recurrence following sinus surgery, which motivated us to study the role of cholecalciferol in preventing recurrence of sinonasal polyposis after endoscopic excision of these polyps. Objective The aim of the work was to study the clinical and radiological outcomes of oral cholecalciferol supplementation after functional endoscopic sinus surgery for recurrent nasal polyposis. Patients and methods A total of 62 patients with recurrent sinonasal polyposis were included in our study during the period from January 2019 to May 2022. The patients underwent functional endoscopic sinus surgery. Overall, 33 patients used oral cholecalciferol postoperatively as group A and 29 patients used oral steroid postoperatively as group B. Patients were scheduled for a follow-up visit (up to 3 months) concerning computed tomographic scan of paranasal sinuses scoring and sinonasal outcome test-22 scoring. Results There were nonsignificant clinical and radiological outcomes of recurrent nasal polyposis in the cholecalciferol group versus the steroid group based on sinonasal outcome test-22 scoring. There was a significant difference in the incidence of adverse effects such as headache, gastric upset, and constipation between both groups. Conclusion Cholecalciferol was studied as a common drug that has fewer adverse effects and is found to be efficient in minimizing outcomes in the recurrence of nasal polyposis after their endoscopic excision.

Keywords

cholecalciferol, endoscopic surgery, nasal polyposis, steroid

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