Does vit. D intake affect severity of allergic rhinitis?

Authors

• Omneya Elsayed Bioumy, Otorhinolaryngology Department, Faculty of Medicine, Benha University, Benha, Egypt
• Ahmed mohammed mahmoud elhewity, Otorhinolaryngology Department, Faculty of Medicine, Benha University, Benha, Egypt
• Nora M. Nassar, Clinical and chemical pathology Department, Faculty of Medicine, Benha University, Benha, Egypt
• Rami Fatouh Abo Elata Tantawy, Otorhinolaryngology Department, Faculty of Medicine, Benha University, Benha, Egypt.Follow

Article Type

Original Study

Subject Area

Rhinology, Allergy

Abstract

Background Vitamin D functions more like a hormone than a simple vitamin, it plays a critical role in "calming" an overactive immune system. Objective Analyze whether adding Vitamin D3 supplementation to Fluticasone nasal spray improves symptoms and control of moderate-to-severe Allergic Rhinitis (AR) compared to Fluticasone alone. Methods one hundred AR cases with vitamin D deficiency were involved in this randomized clinical study. Cases were allocated into 2 groups; group 1 cases were treated with Fluticasone nasal spray, and group 2 cases were treated with Fluticasone nasal spray and cholecalciferol supplementation. Regarding disease severity, the cases were assessed using the Total Nasal Symptom Score (TNSS) and Rhinitis Control Assessment Test score (RCAT). In the two groups, immunoglobulin E (IgE) and vitamin D levels were assessed before and after treatment. Results In the current study, both groups showed improvement after treatment. In group 2. The TNSS was statistically significantly lower in the cases in group 2 (3.36 ± 1.12) compared to group 1 (5.66 ± 1.21). The percentage increase of RCAT was statistically significantly higher in the cases of group 2 (67.9 ± 9.2) compared to group 1 (47.7 ± 5.1). The percentage reduction of IgE was statistically significantly higher in the cases of group 2 (29.8 ± 14.4) as compared to group 1 (22.8 ± 11.4) Conclusion The present study reveals that the use of vitamin D was linked with better symptom relief and AR control than the Fluticasone nasal spray alone.

Keywords

Allergic rhinitis; Vit D deficiency; IgE; Fluticasone

Recommended Citation

Bioumy O, elhewity A, Nassar N, et al. Does vit. D intake affect severity of allergic rhinitis?. Pan Arab J. Rhinol. 2025; 15 : -.
Available at: https://pajr.researchcommons.org/journal/vol15/iss2/14 DOI: https://doi.org/10.58595/2090-7559.1263

Creative Commons License

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