Article Type
Article
Abstract
Background: Allergic fungal rhinosinusitis is an increasingly recognized cause of refractory chronic sinusitis, the clinical and pathological features of such diagnosis remains a matter of conjecture for which several theories have been offered. Most patients experience remittent disease despite corticosteroid therapy and aggressive sinus surgery.
Objective: To present our experience in managing twenty patients with AFS divided into two groups to compare the outcome after addition of oral itraconazol to our treatment protocol.
Methods: Twenty patients with clinically diagnosed (AFS), treated with functional endoscopic sinus surgery followed by postoperative systemic and topical nasal steroids with or without oral itraconazole for at least 3 months.
Results: Significant improvements in the itraconazole arm (group A) were noted regarding the early signs of relapse.
Conclusion: Systemic itraconazol is an effective adjunctive to systemic and topical steroid therapy.
Keywords: Allergic fungal rhinosinusitis, systemic antifungal, management outcome.
Recommended Citation
Abo El Ezz T, Abdelkader H.
Role of postoperative systemic Itraconazole in Management of Allergic Fungal- Rhino Sinusitis (AFS).
Pan Arab J. Rhinol.
2012;
2 : -.
Available at:
https://pajr.researchcommons.org/journal/vol2/iss2/3
