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Article Type

Article

Abstract

Objectives: 1) Learn the bacterial growth and resistance patterns from adenoidectomy specimens 2) correlate growth and resistance patterns with a patient subgroup analysis.

Patients: Children between the ages of 2 months and 12 years undergoing an adenoidectomy at a tertiary academic ambulatory referral surgical center

Methods: Retrospective cohort analysis. Core adenoid tissue was cultured for aerobic and anaerobic bacteria, and bacterial isolates were compared between subgroups

Results: Interestingly, Staph aureus (32%) was grown in higher numbers than S. pneumoniae (23%), M. catarrhalis (19%), or H. influenzae (13%) Sensitivity testing revealed 25% of S. aureus isolates to be methicillin resistant (MRSA, 8% of all patients), and an additional 60% were penicillin resistant (19% of all patients). Qualitative and quantitative analysis of potentially pathogenic bacteria revealed no significant differences between groups, however there was a trend for higher number of MRSA in patients with chronic adenoiditis versus those with adenoid hypertrophy.

Conclusions: Knowledge of common bacteria and resistance patterns guides antimicrobial therapy. Amoxicillin is currently the first-line treatment for many conditions tied directly to adenoid microbiology, therefore the bacteria and resistance patterns of diseased adenoid tissue should be revisited with particular attention to the expanding role of resistant strains of S. aureus.

Keywords: Adenoid, culture, S. aureus, resistance.

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