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Article Type

Article

Abstract

Background and aims: Allergic fungal rhinosinusitis and paranasal sinus fungal balls are two distinct forms of non-invasive fungal rhinosinusitis which affect immunocompetent hosts. Each of them has its specular diagnostic features and hence treatment methods. Our study aims at comparing different ways of diagnosis of allergic fungal sinusitis and sinus fungus ball disease and evaluating methods of treatment of both diseases.

Patients and Methods: It is a prospective study carried out at ENT department, Sohag university hospitals, from March 2011 to January 2013. Forty patients were included in the study. Those patients were divided into two groups: group 1 (24 patients with allergic fungal sinusitis) and group 2 (16 patients with fungal balls). Clinical presentation, laboratory investigations, CT findings, operative findings and postoperative histopathological examination were compared between both groups using statistical analysis.

Results: Statistically significant difference was observed between both groups as regard presence of atopy, clinical presentation and disease laterality, imaging findings and laboratory data. As regard operative findings, each disease has distinct intra-operative findings. Statistical significant difference between both groups was found when we compared Post-operative histopathological examination as well as the possibility for local recurrence.

Conclusions: Both AFS and FB are two categories of fungal sinusitis affect immunocompetant patients but each has different aetiopathology and accordingly different management. Through bacteriology, immunology and CT-scanning it is possible to reach a proper diagnosis and accordingly to start a suitable treatment. A combination of surgical debridement and medical treatment consist of antiallergic drugs is the treatment of choice in AFS while surgery remains the mainstay of treatment for FB without need for medical treatment.

Keywords: allergic fungal sinusitis, fungus balls, diagnosis, histopathology, treatment.

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