Article Type
Article
Abstract
Purpose: The objective of this study was to review clinical outcomes of minimally invasive endoscopic resection (MIER) for anterior skull base (ASB) malignant neoplasms.
Study Design: Retrospective.
Materials and Methods: Data analysis was performed on all patients undergoing MIER from October 2010 to October 2014.
Results: Thirty-one patients with mean age of 54 years underwent MIER. Malignant tumors were managed endoscopically in all cases. Most common histopathologies were squamous cell carcinoma (ten), sinonasal undifferentiated carcinoma (eight), esthesioneuroblastoma (five), and mucosal melanoma (three). Surgical resection (MIER) with curative intent was performed in all cases. Multilayered skull base reconstruction was performed in most patients. American Joint Committee on Cancer tumor staging was used. Twenty five patients were disease free, three patients were dead from disease, and three patients were alive with disease.
Conclusions: This study validated technical feasibility of MIER for different anterior skull base malignant neoplasms. Patients were able to avoid adjunct craniotomy and its complications. MIER resulted in low complication rate and acceptable disease- free survival in patients with advanced tumors.
Keywords: MIER, skull base, malignant neoplasms, endoscopic sinus surgery
Recommended Citation
Elmorsy S, Hassan AM.
Minimally Invasive Endoscopic Resection of Anterior Skull Base malignant Neoplasm.
Pan Arab J. Rhinol.
2015;
5 : -.
Available at:
https://pajr.researchcommons.org/journal/vol5/iss2/3
