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Article Type

Article

Abstract

Objective: Inflammation is a known cause of chronic otitis media with effusion (COME). Neutrophil-lymphocyte and platelet- lymphocyte ratios (NLR, PLR) had been used in COME diagnosis, however there is no complete evidence if this relation exists between the disease itself or its causes as adenoiditis and these parameters Aim is to find if the relation between NLR and PLR and otitis media with effusion, if any reflects the actual relation between the disease itself or adenoiditis as a cause for COME and these parameters.
Materials and Methods: A retrospective-case control- study where data of eighty four pediatric patients with COME who underwent ventilation tube insertion with or without adenoidectomy were collected. A group of 52 healthy children was added as a control group to compare NLR and PLR in both groups. Patients in study group were divided into mucoid subgroup (47 patients) and serous subgroup (37 patients).
Results: Mean NLR was (1.058±0.48, 0.776±0.29) in study and control groups respectively (p value= 0.000). Mean PLR was higher in study than in control group with no significant difference. NLR was (1.2±0.561, 0.87±0.26) in mucoid and serous subgroups respectively (p value 0.001). NLR and PLR in mucoid subgroup were higher than in control group (p value 0.000, 0.028 respectively). NLR and PLR showed no significant difference between adenoidectomy, no- adenoidectomy mucoid subgroup. NLR was higher in no- adenoidectomy than adenoidectomy serous subgroup (1.08±0.22, 0.77±0.22 respectively) (p value 0.000).
Conclusion: NLR and PLR can predict COME. Presence of chronic adenoiditis and need for adenoidectomy did not affect these parameters in the study, reflecting that these parameters are closely related to COME itself and not to adenoiditis as a cause and making these parameters valuable in diagnosis of chronic otitis media with effusion.
Keywords: Neutrophil; lymphocyte; effusion; otitis media.

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